Browse Proteins

Explore nucleic acid-binding proteins and their associated structural information.

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Showing 12 of 43 matching proteins
Reviewed
Viral replication / viral nucleic-acid-related protein
Organism
Severe acute respiratory syndrome coronavirus 2
UniProt ID
P0DTD1
Related PDBs
5saf,6wlc,6wxc,7k1l,7k0r
InterPro family
IPR050534: Replicase polyprotein 1ab-like
InterPro domains
IPR001205: RNA-directed RNA polymerase, C-terminal domain; IPR002589: Macro domain; IPR007094: RNA-directed RNA polymerase, catalytic domain; IPR008740: Peptidase C30, coronavirus; IPR009461: Non-structural protein NSP16, coronavirus-like; IPR009466: Non-structural protein 14, coronavirus; IPR009469: RNA-dependent RNA polymerase, N-terminal, coronavirus; IPR013016: Peptidase C16, coronavirus; IPR014822: Non-structural protein NSP9, coronavirus; IPR014828: Non-structural protein NSP7, coronavirus; IPR014829: Non-structural protein NSP8, coronavirus; IPR018995: RNA synthesis protein NSP10, coronavirus; IPR021590: NSP1, globular domain, betacoronavirus; IPR022733: DPUP/SUD, C-terminal, betacoronavirus; IPR024358: Non-structural protein NSP3, N-terminal, betacoronavirus; IPR024375: Non-structural protein NSP3, SUD-M domain, betacoronavirus; IPR027351: (+) RNA virus helicase core domain; IPR027352: Nonstructural protein 13, zinc-binding domain, coronavirus-like; IPR032505: Non-structural protein NSP4, C-terminal, coronavirus; IPR032592: Non-structural protein NSP3, nucleic acid-binding domain, betacoronavirus; IPR041679: DNA2/NAM7 helicase-like, C-terminal; IPR043606: Coronavirus replicase NSP15, N-terminal oligomerization; IPR043608: Nonstructural protein 15, middle domain, coronavirus; IPR043609: NendoU domain, nidovirus; IPR043610: Non-structural protein 6, coronavirus; IPR043611: Coronavirus replicase NSP3, C-terminal; IPR043612: Non-structural protein NSP4, N-terminal, coronavirus; IPR043613: Non-structural protein 2, C-terminal domain, coronavirus; IPR043615: Nonstructural protein 2, N-terminal domain, coronavirus; IPR044315: Nonstructural protein 14, betacoronavirus; IPR044322: Nonstructural protein 15, middle domain, alpha/betacoronavirus; IPR044330: Nonstructural protein 15, N-terminal domain, alpha/beta-coronavirus; IPR044343: Nonstructural protein 13, 1B domain, coronavirus; IPR044351: RNA-dependent RNA polymerase, SARS-CoV-like; IPR044353: NSP3, second ubiquitin-like (Ubl) domain, coronavirus; IPR044357: NSP3, first ubiquitin-like (Ubl) domain, coronavirus; IPR044367: Non-structural protein 6, betacoronavirus; IPR044371: Non-structural protein 3, X-domain-like; IPR044389: Non-structural protein 2, SARS-CoV-like; IPR044401: NSP15, NendoU domain, coronavirus; IPR044863: Nidovirus RdRp-associated nucleotidyl transferase (NiRAN) domain; IPR044864: Non-structural protein NSP3, SUD-N (Mac2) domain, betacoronavirus; IPR046435: NSP14, guanine-N7-methyltransferase domain, coronavirus; IPR046436: Nidovirus 3'-5' exoribonuclease domain; IPR046438: Nidovirus 2-O-methyltransferase; IPR046440: Arterivirus Nsp11 N-terminal/Coronavirus NSP15 middle domain; IPR046441: RNA-dependent RNA polymerase, coronavirus; IPR046442: NSP1, C-terminal domain, betacoronavirus; IPR046443: NSP1, globular domain, alpha/betacoronavirus; IPR047566: Coronavirus replicase NSP3, Y domain; IPR047567: Non-structural protein NSP3, group 2-specific marker domain, betacoronavirus; IPR047570: NSP12, interface domain, coronavirus; IPR047573: Non-structural protein 2, middle domain, coronavirus; IPR048672: Nonstructural protein 13, zinc-binding domain, coronavirus; IPR048673: Nonstructural protein 13, stalk domain, coronavirus; IPR049894: Coronavirus NSP3, 3Ecto domain
Matched classes
CRISPR-Cas / prokaryotic antiviral defense protein [cas ] || Viral replication / viral nucleic-acid-related protein [betacoronavirus, coronavirus, polyprotein 1ab, rdrp, replicase, rna-dependent rna polymerase, viral] || DNA/RNA polymerase and replication protein [polymerase, replicase, rna polymerase, rna-dependent rna polymerase] || Nuclease / DNA-RNA repair enzyme [nuclease, ribonuclease] || DNA/RNA modification or nucleotide metabolism enzyme [methyltransferase, nucleoside] || Other enzyme / miscellaneous [peptidase]
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Reviewed
Transcription factor / transcription regulator
Organism
Escherichia coli (strain K12)
UniProt ID
P00579
Related PDBs
4kn7,4kn4,5uah,6byu,6cux,6n58,6n57,6psv,6psq,6psu,6psr,6pst
InterPro family
IPR028630: RNA polymerase sigma factor RpoD; IPR050239: Sigma-70 factor family, RNA polymerase initiation factors
InterPro domains
IPR000943: RNA polymerase sigma-70; IPR007127: RNA polymerase sigma factor 70, region 1.1; IPR007624: RNA polymerase sigma-70 region 3; IPR007627: RNA polymerase sigma-70 region 2; IPR007630: RNA polymerase sigma-70 region 4; IPR007631: RNA polymerase sigma factor 70, non-essential domain; IPR009042: RNA polymerase sigma-70 region 1.2; IPR012760: RNA polymerase sigma factor RpoD, C-terminal; IPR014284: RNA polymerase sigma-70-like domain
Matched classes
DNA/RNA polymerase and replication protein [polymerase, rna polymerase] || Translation / ribosomal protein [initiation factor] || Transcription factor / transcription regulator [rna polymerase initiation factor, rpod, sigma factor, sigma-70]
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Reviewed
RNA-binding / RNA metabolism protein
Organism
Escherichia coli (strain K12)
UniProt ID
P0A6X3
Related PDBs
3qo3,3res,6qlb
InterPro family
IPR005001: RNA-binding protein Hfq
InterPro domains
IPR047575: Sm domain
Matched classes
RNA-binding / RNA metabolism protein [hfq, rna-binding]
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Reviewed
RNA-binding / RNA metabolism protein
Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
UniProt ID
Q9HUM0
Related PDBs
3qui,4j5y,4j6w,4j6x
InterPro family
IPR005001: RNA-binding protein Hfq
InterPro domains
IPR047575: Sm domain
Matched classes
RNA-binding / RNA metabolism protein [hfq, rna-binding]
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Reviewed
Translation / ribosomal protein
Organism
Escherichia coli (strain K12)
UniProt ID
P10121
Related PDBs
6cs8,6cvd,6dlx
InterPro family
IPR004390: Signal-recognition particle receptor FtsY
InterPro domains
IPR000897: Signal recognition particle, SRP54 subunit, GTPase domain; IPR003593: AAA+ ATPase domain; IPR013822: Signal recognition particle SRP54, helical bundle
Matched classes
Translation / ribosomal protein [ftsy, signal-recognition particle, srp receptor] || DNA/RNA modification or nucleotide metabolism enzyme [nucleoside]
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Reviewed
Translation / ribosomal protein
Organism
Escherichia coli (strain K12)
UniProt ID
P0A7R5
Related PDBs
3d3b
InterPro family
IPR001848: Small ribosomal subunit protein uS10
InterPro domains
IPR027486: Small ribosomal subunit protein uS10 domain
Matched classes
Translation / ribosomal protein [ribosomal]
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Reviewed
RNA-binding / RNA metabolism protein
Organism
Homo sapiens
UniProt ID
O75533
Related PDBs
3lqv,5zya,6en4,7b0i,7b91,7b92,7b9c,7evo,7opi,7onb,7omf,8hk1
InterPro family
IPR038737: Splicing factor 3B subunit 1-like
InterPro domains
IPR015016: Splicing factor 3B subunit 1; IPR054573: Phosphatase PP2A regulatory subunit A/Splicing factor 3B subunit 1-like, HEAT repeat
Matched classes
RNA-binding / RNA metabolism protein [splicing factor]
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Reviewed
RNA-binding / RNA metabolism protein
Organism
Homo sapiens
UniProt ID
Q9Y3B4
Related PDBs
3lqv
InterPro family
—
InterPro domains
IPR000504: RNA recognition motif domain; IPR034150: SF3B6, RNA recognition motif
Matched classes
RNA-binding / RNA metabolism protein [rna-binding, sf3b] || DNA/RNA modification or nucleotide metabolism enzyme [nucleotide]
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Reviewed
RNA-binding / RNA metabolism protein
Organism
Homo sapiens
UniProt ID
Q5VYS8
Related PDBs
5w0n
InterPro family
—
InterPro domains
IPR001878: Zinc finger, CCHC-type; IPR002058: PAP/25A-associated; IPR003604: Matrin/U1-C-like, C2H2-type zinc finger; IPR045100: Terminal uridylyltransferase 4/7, nucleotidyltransferase domain; IPR054708: Poly(A) RNA polymerase, mitochondrial-like, central palm domain
Matched classes
DNA/RNA polymerase and replication protein [nucleotidyltransferase, polymerase, rna polymerase]
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Reviewed
RNA-binding / RNA metabolism protein
Organism
Drosophila melanogaster
UniProt ID
Q9VI58
Related PDBs
5z4m,6i0s
InterPro family
—
InterPro domains
IPR054708: Poly(A) RNA polymerase, mitochondrial-like, central palm domain
Matched classes
DNA/RNA polymerase and replication protein [nucleotidyltransferase, polymerase, rna polymerase]
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Reviewed
tRNA-related enzyme
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
UniProt ID
P07236
Related PDBs
4eo4
InterPro family
IPR002320: Threonine-tRNA ligase, class IIa
InterPro domains
IPR002314: Aminoacyl-tRNA synthetase, class II (G/ P/ S/T); IPR004154: Anticodon-binding; IPR006195: Aminoacyl-tRNA synthetase, class II; IPR033728: Threonine-tRNA ligase catalytic core domain; IPR047246: Threonine-tRNA ligase, class IIa, anticodon-binding domain
Matched classes
RNA-binding / RNA metabolism protein [rna ligase] || tRNA-related enzyme [aminoacyl, threonine-trna ligase, trna, trna ligase]
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Reviewed
RNA-binding / RNA metabolism protein
Organism
Escherichia coli (strain K12)
UniProt ID
P0AG30
Related PDBs
9ff7
InterPro family
IPR004665: Transcription termination factor Rho
InterPro domains
IPR000194: ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain; IPR003593: AAA+ ATPase domain; IPR011112: Rho termination factor-like, N-terminal; IPR011113: Rho termination factor, RNA-binding domain; IPR011129: Cold-shock domain; IPR041703: Transcription termination factor Rho, ATP binding domain
Matched classes
RNA-binding / RNA metabolism protein [rho, rna-binding, transcription termination factor] || DNA/RNA modification or nucleotide metabolism enzyme [nucleoside, nucleotide]
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